3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole

Name: 3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1192-80-9
Cat. No. CS-0075702
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole|CS-0075702

Structure of 1192-80-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1192-80-9
Cat. No. CS-0075702
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₅ClN₂O
Molecular Weight 132.55
Synonym(s) 3-Chloromethyl-5-methyl-[1,2,4]oxadiazole
SMILES ClCC1=NOC(C)=N1

Description

This oxadiazole derivative features a chloromethyl group enabling direct functionalization in synthetic workflows. The methyl substituent enhances stability and modulates reactivity, while the heterocyclic core provides a rigid, electron-deficient scaffold. Ideal for coupling reactions and bioconjugation under standard conditions.

Application

3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole serves as a versatile synthetic building block for the introduction of electrophilic chloromethyl groups under mild conditions. Its reactivity enables efficient functionalization in nucleophilic substitution reactions, facilitating the construction of complex heterocyclic architectures. The molecule exhibits good bench stability and compatibility with diverse functional groups, making it valuable for medicinal chemistry campaigns and process-scale synthesis where selective C–C or C–N bond formation is required.

Synthesis

Route1
- 108-24-7
- 3272-96-6
- ~22%
- In-stock
  
  1192-80-9
References
- ASTRAZENECA AB; NPS PHARMACEUTICALS, INC. Patent: WO2004/14902 A2, 2004 ; Location in patent: Page 43 ; WO 2004/014902 A2
Route2
- 3272-96-6
- ~%
- In-stock
  
  1192-80-9
References
- US5428047 A1, ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 3265
Class : 8	Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 38.92
LogP 1.11682
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Oxadiazole compounds

Key Words

1192-80-9 sigma1192-80-9 manufacturer1192-80-9 price1192-80-9 structure1192-80-9 SDSbuy 1192-80-91192-80-9 supplier1192-80-9 uses1192-80-9 molecular weightprice of 1192-80-91192-80-9 chemical name formula of 1192-80-9

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole

CAS No. 1192-80-9

Recommended Products