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Structure of 119162-53-7
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3-(4-Bromophenyl)isoxazol-5-amine features a brominated phenyl group attached to an isoxazole core bearing a primary amine. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering a handle for downstream functionalization via amine-directed coupling. The molecule exhibits bench-stable handling and compatibility with standard synthetic protocols.
3-(4-Bromophenyl)isoxazol-5-amine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient construction of pharmaceutical scaffolds via palladium-catalyzed cross-coupling reactions. The bromo group facilitates Suzuki, Stille, and Negishi transformations, while the isoxazol-5-amine moiety offers hydrogen-bonding capacity and metabolic stability. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthetic sequences requiring orthogonal reactivity and functional group compatibility.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: