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Structure of 1191063-90-7
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This boronate ester integrates a carboxylic acid handle for direct conjugation, enabling efficient Suzuki-Miyaura coupling under standard conditions. The tetramethyl-dioxaborolane moiety provides exceptional stability and moisture tolerance, simplifying handling and storage. Ideal for bioconjugation and probe synthesis.
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propanoic acid serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its carboxylic acid functionality enables direct incorporation into bioactive molecules and heterocyclic scaffolds. The tetramethyl-substituted dioxaborolane enhances air stability and minimizes protodeboronation, facilitating reliable coupling with aryl, vinyl, and heteroaryl halides under standard conditions. Ideal for medicinal chemistry campaigns requiring efficient C–C bond formation and orthogonal functional group handling.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: