Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Name: Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1150561-77-5
Cat. No. CS-0153820
Purity≥98%
MDL No.MFCD10700159

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate|CS-0153820

Structure of 1150561-77-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1150561-77-5
Cat. No. CS-0153820
Purity ≥98%
MDL No. MFCD10700159
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₉BO₄
Molecular Weight 214.07
Synonym(s) Methyl 3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl) propionate
SMILES CC1(C)C(C)(C)OB(CCC(=O)OC)O1

Description

Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate is a bench-stable boronate ester featuring a terminal methyl ester group. This structure enables direct coupling in Suzuki-Miyaura reactions, streamlining the synthesis of functionalized alkenes and aromatic derivatives. The tetramethyl-substituted dioxaborolane enhances stability and minimizes side reactions during handling and storage.

Application

Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate moiety enables efficient coupling with aryl and vinyl halides under mild conditions, while the ester group provides a handle for downstream functionalization. Its excellent stability, low toxicity, and ease of purification make it a practical choice for constructing complex molecular architectures in medicinal chemistry and materials science workflows.

Synthesis

Route1
- 292638-85-8
- In-stock
  
  73183-34-3
- ~92%
- In-stock
  
  1150561-77-5
References
- LEK Pharmaceuticals d.d.; The designation of the inventor has not yet been filed Patent: EP2647640 A1, 2013 ; Location in patent: Paragraph 0072; 0073 ;
Route2
- 67-56-1
- 292638-85-8
- In-stock
  
  73183-34-3
- ~83%
- In-stock
  
  1150561-77-5
References
- Knott, Kenneth; Fishovitz, Jennifer; Thorpe, Steven B.; Lee, Irene; Santos, Webster L. Organic and Biomolecular Chemistry, 2010 , vol. 8, # 15 p. 3451 - 3456

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 44.76
LogP 1.6417
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 3

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Other aliphatic heterocycles compounds

Key Words

1150561-77-5 sigma1150561-77-5 manufacturer1150561-77-5 price1150561-77-5 structure1150561-77-5 SDSbuy 1150561-77-51150561-77-5 supplier1150561-77-5 uses1150561-77-5 molecular weightprice of 1150561-77-51150561-77-5 chemical name formula of 1150561-77-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

CAS No. 1150561-77-5

Recommended Products