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CS-W001157 4
Total: USD 88.00

2-Fluoro-4-methoxynicotinic acid

  • CAS No. 1190315-81-1

  • Cat. No. CS-0150621
  • Purity≥97%
  • MDL No.MFCD12828253

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-4-methoxynicotinic acid|CS-0150621

Structure of 1190315-81-1

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General Information

  • CAS No. 1190315-81-1
  • Cat. No. CS-0150621
  • Purity ≥97%
  • MDL No. MFCD12828253
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆FNO₃
  • Molecular Weight 171.13
  • Synonym(s) None
  • SMILES COC1=C(C(=NC=C1)F)C(=O)O

Description

2-Fluoro-4-methoxynicotinic acid is a fluorinated pyridine carboxylic acid featuring a methoxy group at the 4-position and a fluorine atom at the 2-position. This electronic modulation enhances its utility in medicinal chemistry, where it serves as a key scaffold for bioactive compounds. The molecule exhibits good stability under standard conditions and integrates readily into diverse synthetic pathways.

Application

2-Fluoro-4-methoxynicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive compounds. Its orthogonal functional groups—fluorine at C2 and methoxy at C4—facilitate selective derivatization and coupling reactions. The carboxylic acid moiety supports direct amidation, esterification, or activation for peptide-like linkages, offering robust utility in API development and scaffold diversification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.9275
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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