4-Chloro-1H-pyrrolo[2,3-c]pyridine

Name: 4-Chloro-1H-pyrrolo[2,3-c]pyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1188313-15-6
Cat. No. CS-0020014
Purity≥98%
MDL No.MFCD16657181

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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4-Chloro-1H-pyrrolo[2,3-c]pyridine|CS-0020014

Structure of 1188313-15-6

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Description

4-Chloro-1H-pyrrolo[2,3-c]pyridine is a heterocyclic scaffold featuring a chlorinated pyrrolopyridine core with intrinsic electron-deficiency and enhanced stability. This platform integrates readily into synthetic sequences for medicinal chemistry, offering a robust building block for kinase inhibitors and bioactive molecule discovery under standard conditions.

Application

4-Chloro-1H-pyrrolo[2,3-c]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to nitrogen-rich scaffolds via palladium-catalyzed cross-coupling reactions. Its chloro group facilitates reliable functionalization under standard conditions, while the fused pyrrole-pyridine core offers enhanced metabolic stability and predictable electronic properties. The compound exhibits excellent bench stability and compatibility with common protecting groups, making it ideal for modular synthesis of kinase inhibitors and other bioactive molecules.

General Information

CAS No. 1188313-15-6
Cat. No. CS-0020014
Purity ≥98%
MDL No. MFCD16657181
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅ClN₂
Molecular Weight 152.58
Synonym(s) 4-Chloro-1H-pyrrolo(2,3-C)pyridine
SMILES ClC1=CN=CC2=C1C=CN2

Computational Chemistry Data

TPSA 28.68
LogP 2.2163
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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4-Chloro-1H-pyrrolo[2,3-c]pyridine

CAS No. 1188313-15-6

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