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3-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine hydrochloride

  • CAS No. 1188265-60-2

  • Cat. No. CS-0161051
  • Purity≥95%
  • MDL No.MFCD13152217

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine hydrochloride|CS-0161051

Structure of 1188265-60-2

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General Information

  • CAS No. 1188265-60-2
  • Cat. No. CS-0161051
  • Purity ≥95%
  • MDL No. MFCD13152217
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉BrClN₃
  • Molecular Weight 238.51
  • Synonym(s) 3-BROMO-5,6,7,8-TETRAHYDROIMIDAZO[1,5-A]PYRAZINEHYDROCHLORIDE
  • SMILES BrC1=NC=C2CNCCN21.[H]Cl

Description

This bench-stable hydrochloride salt features a fused imidazo[1,5-a]pyrazine core with a brominated tetrahydro ring, enabling direct incorporation into transition-metal-catalyzed cross-coupling reactions. The protonated nitrogen enhances solubility in polar media while maintaining stability under standard handling conditions.

Application

3-Bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine hydrochloride serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its brominated position enables palladium-catalyzed cross-coupling reactions, while the saturated imidazopyrazine core provides structural rigidity and favorable physicochemical properties. The hydrochloride salt enhances solubility and stability, facilitating handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.85
  • LogP   1.1706
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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