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2-Amino-2-(pyridin-2-yl)ethanol dihydrochloride

  • CAS No. 1187930-63-7

  • Cat. No. CS-0089917
  • Purity≥98%
  • MDL No.MFCD12913795

*For research and further manufacturing use only, not for direct human use.

2-Amino-2-(pyridin-2-yl)ethanol dihydrochloride|CS-0089917

Structure of 1187930-63-7

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General Information

  • CAS No. 1187930-63-7
  • Cat. No. CS-0089917
  • Purity ≥98%
  • MDL No. MFCD12913795
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂Cl₂N₂O
  • Molecular Weight 211.09
  • Synonym(s) 2-Amino-2-(2-pyridyl)ethanol dihydrochloride
  • SMILES NC(C1=CC=CC=N1)CO.Cl.Cl

Description

2-Amino-2-(pyridin-2-yl)ethanol dihydrochloride features a pyridine ring linked to an aminoethanol backbone, delivering a bifunctional scaffold with enhanced solubility and stability. The protonated amine groups facilitate efficient salt formation, improving handling and crystallization properties. This compound serves as a key intermediate in the synthesis of bioactive heterocycles and ligands for metal coordination.

Application

2-Amino-2-(pyridin-2-yl)ethanol dihydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its bifunctional architecture—combining a primary amine and a β-hydroxyl group on a pyridine-bearing backbone—facilitates straightforward derivatization via alkylation, acylation, or cyclization reactions. The dihydrochloride salt enhances solubility and bench stability, simplifying handling and purification in synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.14
  • LogP   0.9173
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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