Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-(2,2-Difluorocyclopropyl)-1h-pyrazol-3-amine

  • CAS No. 1186609-07-3

  • Cat. No. CS-0309632
  • Purity≥97%
  • MDL No.MFCD28362806

*For research and further manufacturing use only, not for direct human use.

5-(2,2-Difluorocyclopropyl)-1h-pyrazol-3-amine|CS-0309632

Structure of 1186609-07-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1186609-07-3
  • Cat. No. CS-0309632
  • Purity ≥97%
  • MDL No. MFCD28362806
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇F₂N₃
  • Molecular Weight 159.14
  • Synonym(s) None
  • SMILES NC1=NNC(=C1)C1CC1(F)F

Description

This pyrazole derivative features a 2,2-difluorocyclopropyl group that enhances metabolic stability and lipophilicity. The amine functionality at the C3 position enables direct coupling in medicinal chemistry campaigns. Designed for synthetic accessibility, it integrates readily into bioactive scaffolds requiring constrained cyclopropyl motifs with tunable electronic properties.

Application

5-(2,2-Difluorocyclopropyl)-1H-pyrazol-3-amine serves as a versatile building block for medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling reactions. The difluorocyclopropyl group imparts enhanced metabolic stability and modulates electronic properties, while the pyrazole amine functionality facilitates facile derivatization via amidation, alkylation, or transition-metal-catalyzed cross-coupling. Its bench-stable solid form and compatibility with diverse reaction conditions make it well-suited for iterative synthesis campaigns in drug discovery.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   54.7
  • LogP   1.1145
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1186609-07-3 sigma1186609-07-3 manufacturer1186609-07-3 price1186609-07-3 structure1186609-07-3 SDSbuy 1186609-07-31186609-07-3 supplier1186609-07-3 uses1186609-07-3 molecular weightprice of 1186609-07-31186609-07-3 chemical name formula of 1186609-07-3
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label