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CS-W001157 4
Total: USD 88.00

(3-Bromo-5-chlorophenyl)boronic acid

  • CAS No. 1186403-17-7

  • Cat. No. CS-0060189
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-Bromo-5-chlorophenyl)boronic acid|CS-0060189

Structure of 1186403-17-7

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General Information

  • CAS No. 1186403-17-7
  • Cat. No. CS-0060189
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BBrClO₂
  • Molecular Weight 235.27
  • Synonym(s) 3-Bromo-5-Chlorophenylboronicacid
  • SMILES C1=C(C=C(C=C1Br)Cl)B(O)O

Description

(3-Bromo-5-chlorophenyl)boronic acid features a dual halogenated aryl scaffold enabling efficient cross-coupling in Suzuki-Miyaura reactions. The boronic acid moiety integrates readily into complex molecular architectures, while the bromo and chloro substituents offer orthogonal reactivity for sequential functionalization. This compound exhibits bench-stable handling and compatibility with diverse reaction conditions.

Application

(3-Bromo-5-chlorophenyl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki-Miyaura conditions. Its compatibility with both bromo and chloro leaving groups allows for sequential functionalization or selective coupling in complex molecule synthesis. The boronic acid moiety offers excellent bench stability, ease of purification, and tolerance to a range of functional groups, making it well-suited for applications in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.7823
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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