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CS-W001157 4
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2-Isopropyl-4-(methylaminomethyl)thiazole dihydrochloride

  • CAS No. 1185167-55-8

  • Cat. No. CS-D1758
  • Purity≥98%
  • MDL No.MFCD11841218

*For research and further manufacturing use only, not for direct human use.

2-Isopropyl-4-(methylaminomethyl)thiazole dihydrochloride|CS-D1758

Structure of 1185167-55-8

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General Information

  • CAS No. 1185167-55-8
  • Cat. No. CS-D1758
  • Purity ≥98%
  • MDL No. MFCD11841218
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆Cl₂N₂S
  • Molecular Weight 243.20
  • Synonym(s) N-Methyl-2-(1-methylethyl)-4-thiazolemethanamine dihydrochloride
  • SMILES CC(C1=NC(CNC)=CS1)C.Cl.Cl

Description

2-Isopropyl-4-(methylaminomethyl)thiazole dihydrochloride delivers a stable, moisture-tolerant thiazole scaffold bearing a basic methylaminomethyl side chain. This compound integrates readily into medicinal chemistry libraries, offering enhanced solubility and metabolic stability for target-directed synthesis.

Application

2-Isopropyl-4-(methylaminomethyl)thiazole dihydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds. Its dual functionalization—bulky isopropyl and methylaminomethyl groups—provides steric and electronic modulation for target engagement. The dihydrochloride salt enhances solubility and stability, facilitating handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   2.8295
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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