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Structure of 1184172-46-0
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2-Chloro-3-fluoro-4-hydroxypyridine features a strategically positioned hydroxyl group flanked by chlorine and fluorine substituents, enabling direct functionalization in heterocyclic synthesis. This electron-deficient pyridine scaffold integrates readily into bioactive molecules, offering enhanced reactivity for C–H activation and cross-coupling processes under mild conditions.
2-Chloro-3-fluoro-4-hydroxypyridine serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the pyridine ring due to orthogonal reactivity of its chloro and fluoro substituents. The hydroxyl group provides a handle for derivatization or metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with palladium-mediated cross-coupling protocols make it a practical choice for constructing complex pharmaceutical scaffolds and bioactive heterocycles.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: