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CS-W001157 4
Total: USD 88.00

2'-Hydroxyacetophenone

  • CAS No. 118-93-4

  • Cat. No. CS-W020051
  • Purity≥98%
  • MDL No.MFCD00002219

*For research and further manufacturing use only, not for direct human use.

2'-Hydroxyacetophenone|CS-W020051

Structure of 118-93-4

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General Information

  • CAS No. 118-93-4
  • Cat. No. CS-W020051
  • Purity ≥98%
  • MDL No. MFCD00002219
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₂
  • Molecular Weight 136.15
  • Synonym(s) o-Hydroxyacetophenone; o-Acetylphenol
  • SMILES CC(C1=CC=CC=C1O)=O

Description

Silicon amine protocol (SLAP) reagents, in conjunction with aldehydes and ketones, form N-unprotected piperazines via photocatalytic cross-coupling with Ir[(ppy)2dtbbpy]PF6 (747769). Heteroaromatic, aromatic, and aliphatic aldehydes are well tolerated, as are structurally and stereochemically complex SLAP reagents. This product was introduced in collaboration with the Bode Research Group and provides a tin-free alternative to SnAP (tin amine protocol) reagents for piperazine synthesis.

Synthesis

  • Route1
    • null|null
      87804-23-7
    • ~93%
    • In-stock
      2'-Hydroxyacetophenone|CS-W020051
      118-93-4

    References

    • Eshtiagh-Hosseini, Hossein; Tabari, Taymaz; Takjoo, Reza; Eshghi, Hossein Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2013 , vol. 43, # 3 p. 264 - 272
  • Route2
    • null|null
      120820-40-8
    • ~91%
    • In-stock
      2'-Hydroxyacetophenone|CS-W020051
      118-93-4

    References

    • Curini, Massimo; Epifano, Francesco; Marcotullio, Maria Carla; Rosati, Ornelio; Rossi, Monia; Tsadjout, Andre Synthetic Communications, 2000 , vol. 30, # 17 p. 3181 - 3187
  • Route3
    • 1-(2-(Allyloxy)phenyl)ethan-1-one|CS-0322971
      53327-14-3
    • ~90%
    • In-stock
      2'-Hydroxyacetophenone|CS-W020051
      118-93-4

    References

    • Humne, Vivek; Lokahnde, Pradeep Synthetic Communications, 2014 , vol. 44, # 7 p. 929 - 935

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.5948
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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