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CS-W001157 4
Total: USD 88.00

5-Cyclopropyl-1-methyl-1H-pyrazole-3-carboxylic acid

  • CAS No. 1177291-38-1

  • Cat. No. CS-0075838
  • Purity≥98%
  • MDL No.MFCD09965808

*For research and further manufacturing use only, not for direct human use.

5-Cyclopropyl-1-methyl-1H-pyrazole-3-carboxylic acid|CS-0075838

Structure of 1177291-38-1

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General Information

  • CAS No. 1177291-38-1
  • Cat. No. CS-0075838
  • Purity ≥98%
  • MDL No. MFCD09965808
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) None
  • SMILES O=C(O)C(C=C1C2CC2)=NN1C

Description

5-Cyclopropyl-1-methyl-1H-pyrazole-3-carboxylic acid features a sterically constrained cyclopropyl group and a methyl-substituted pyrazole core, delivering enhanced metabolic stability. The carboxylic acid functionality enables direct coupling in peptide synthesis or conjugation workflows. This scaffold exhibits favorable solubility under standard conditions and serves as a key building block for bioactive heterocycles in medicinal chemistry.

Application

5-Cyclopropyl-1-methyl-1H-pyrazole-3-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its carboxylic acid functionality facilitates direct coupling reactions and derivatization under standard conditions. The cyclopropyl and methyl substituents enhance metabolic stability and modulate lipophilicity, offering favorable physicochemical properties for drug discovery applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.9957
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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