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CS-W001157 4
Total: USD 88.00

Dexamethasone acetate

  • CAS No. 1177-87-3

  • Cat. No. CS-1941
  • Purity≥98%
  • MDL No.MFCD00027407

*For research and further manufacturing use only, not for direct human use.

Dexamethasone acetate|CS-1941

Structure of 1177-87-3

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General Information

  • CAS No. 1177-87-3
  • Cat. No. CS-1941
  • Purity ≥98%
  • MDL No. MFCD00027407
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₃₁FO₆
  • Molecular Weight 434.50
  • Synonym(s) Dexamethasone 21-acetate; Hexadecadrol acetate
  • SMILES C[C@@]1([C@@]2(O)C(COC(C)=O)=O)[C@](C[C@H]2C)([H])[C@@](CCC3=CC4=O)([H])[C@@](F)([C@]3(C=C4)C)[C@@H](O)C1

Description

.

Application

Dexamethasone acetate serves as a potent synthetic glucocorticoid steroid with established anti-inflammatory and immunosuppressive properties. Its acetylated form enhances metabolic stability and facilitates handling in pharmaceutical formulations. The molecule enables targeted delivery in topical, injectable, and systemic applications, offering consistent bioavailability and predictable pharmacokinetics. Dexamethasone acetate functions as a reliable building block in corticosteroid research and clinical development workflows.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 80, p. 3160
  • Route2
    • Betamethasone acetate impurity 2|CS-0854708
      912-38-9
    • ~%
    • In-stock
      Dexamethasone acetate|CS-1941
      1177-87-3

    References

    • Journal of the American Chemical Society, , vol. 80, p. 4431
  • Route3
    • null|null
      34542-57-9
    • ~%
    • In-stock
      Dexamethasone acetate|CS-1941
      1177-87-3

    References

    • Journal of the American Chemical Society, , vol. 80, p. 3160

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H360
Precautionary Statements : P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.9
  • LogP   2.4665
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   3

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