Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,3-Difluoro-5-methylbenzene

  • CAS No. 117358-51-7

  • Cat. No. CS-W013474
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,3-Difluoro-5-methylbenzene|CS-W013474

Structure of 117358-51-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 117358-51-7
  • Cat. No. CS-W013474
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆F₂
  • Molecular Weight 128.12
  • Synonym(s) 3,5-Difluorotoluene
  • SMILES CC1=CC(F)=CC(F)=C1

Description

1,3-Difluoro-5-methylbenzene is a fluorinated aromatic compound featuring complementary electron-withdrawing fluorine atoms and a methyl group positioned for steric and electronic modulation. This substitution pattern enables selective functionalization in synthetic routes requiring balanced reactivity and stability under standard conditions.

Application

1,3-Difluoro-5-methylbenzene serves as a valuable building block for fluorinated aromatic scaffolds, enabling direct functionalization at the electron-rich methyl-substituted position. Its orthogonal reactivity profile facilitates palladium-catalyzed cross-couplings and electrophilic substitutions under mild conditions, with the difluoro pattern enhancing metabolic stability in bioactive molecule design. Bench-stable and amenable to purification via standard distillation or chromatography, it functions effectively in medicinal chemistry lead optimization and agrochemical development workflows.

Synthesis

  • Route1
    • null|null
      141776-91-2
    • ~%
    • In-stock
      1,3-Difluoro-5-methylbenzene|CS-W013474
      117358-51-7

    References

    • US6235764 B1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS08,GHS09
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅱ
Hazard Statements : H225-H304-H315-H336-H361-H373-H411
Precautionary Statements : P210-P260-P280-P331

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   0
  • LogP   2.27322
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,3-Difluoro-5-methylbenzene sigma1,3-Difluoro-5-methylbenzene manufacturer1,3-Difluoro-5-methylbenzene price1,3-Difluoro-5-methylbenzene structure1,3-Difluoro-5-methylbenzene SDSbuy 1,3-Difluoro-5-methylbenzene1,3-Difluoro-5-methylbenzene supplier1,3-Difluoro-5-methylbenzene uses1,3-Difluoro-5-methylbenzene molecular weightprice of 1,3-Difluoro-5-methylbenzene1,3-Difluoro-5-methylbenzene chemical name formula of 1,3-Difluoro-5-methylbenzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label