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CS-W001157 4
Total: USD 88.00

3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride

  • CAS No. 1172097-47-0

  • Cat. No. CS-W000162
  • Purity≥95%
  • MDL No.MFCD09971722
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride|CS-W000162

Structure of 1172097-47-0

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Description

3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride delivers a rigid, strain-engineered scaffold with a polar amine and carboxylic acid functionality. This bench-stable derivative features enhanced solubility and predictable conformational behavior, enabling efficient incorporation into bioactive molecules and peptidomimetics under standard conditions.

Application

3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride serves as a rigid, conformationally constrained building block for medicinal chemistry and peptide mimicry. Its bicyclic scaffold imparts high metabolic stability and defined spatial orientation, enabling precise placement of pharmacophoric elements. The amine and carboxylic acid functionalities offer direct handles for derivatization via standard coupling reactions, while the hydrochloride salt ensures excellent solubility and bench stability. This compound facilitates rapid access to diverse heterocyclic scaffolds and is particularly useful in fragment-based drug discovery campaigns requiring compact, three-dimensional architectures.

General Information

  • CAS No. 1172097-47-0
  • Cat. No. CS-W000162
  • Purity ≥95%
  • MDL No. MFCD09971722
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀ClNO₂
  • Molecular Weight 163.60
  • Synonym(s) None
  • SMILES Cl.O=C(O)C12CC(N)(C1)C2

Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.3742
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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