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CS-W001157 4
Total: USD 88.00

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoxaline

  • CAS No. 1167418-13-4

  • Cat. No. CS-0006081
  • Purity≥98%
  • MDL No.MFCD11054040

*For research and further manufacturing use only, not for direct human use.

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoxaline|CS-0006081

Structure of 1167418-13-4

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General Information

  • CAS No. 1167418-13-4
  • Cat. No. CS-0006081
  • Purity ≥98%
  • MDL No. MFCD11054040
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₇BN₂O₂
  • Molecular Weight 256.11
  • Synonym(s) Quinoxaline-6-boronic acid picol ester
  • SMILES CC1(C)C(C)(C)OB(C2=CC=C3N=CC=NC3=C2)O1

Application

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoxaline serves as a robust boronate building block for Suzuki-Miyaura cross-coupling reactions. Its quinoxaline core provides a rigid, electron-deficient heterocyclic scaffold with established utility in medicinal chemistry and materials science. The tetramethylboronate group offers excellent bench stability, mild reaction conditions, and broad functional group tolerance, enabling efficient late-stage diversification of complex molecular architectures.

Synthesis

  • Route1

    References

    • PRESIDENT AND FELLOWS OF HARVARD COLLEGE; RITTER, Tobias; FURUYA, Takeru; TANG, Pingping Patent: WO2010/59943 A2, 2010 ; Location in patent: Page/Page column 86 ;

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   44.24
  • LogP   1.929
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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