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CS-W001157 4
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4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine

  • CAS No. 941685-26-3

  • Cat. No. CS-D0223
  • Purity≥98%
  • MDL No.MFCD11857752

*For research and further manufacturing use only, not for direct human use.

4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine|CS-D0223

Structure of 941685-26-3

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General Information

  • CAS No. 941685-26-3
  • Cat. No. CS-D0223
  • Purity ≥98%
  • MDL No. MFCD11857752
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈ClN₃OSi
  • Molecular Weight 283.83
  • Synonym(s) 4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl-7H-pyrrolo[2,3-d]pyrimidine
  • SMILES C[Si](CCOCN1C=CC2=C(Cl)N=CN=C21)(C)C

Synthesis

  • Route1
    • null|null
      76513-69-4
    • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Tofacitinib Impurity|CS-0213936
      3680-69-1
    • ~90%
    • In-stock
      4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine|CS-D0223
      941685-26-3

    References

    • Zhou, Jiacheng; Liu, Pingli; Lin, Qiyan; Metcalf, Brian W.; Meloni, David; Pan, Yongchun; Xia, Michael; Li, Mei; Yue, Tai-Yuen; Rodgers, James D.; Wang, Haisheng Patent: US2010/190981 A1, 2010 ; Location in patent: Page/Page column 73 ; US 20100190981 A1
  • Route2
    • 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol-1|CS-0655283
      7400-06-8
    • ~%
    • In-stock
      4-Chloro-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine|CS-D0223
      941685-26-3

    References

    • Bioorganic and Medicinal Chemistry, , vol. 20, # 22 p. 6770 - 6789
  • Route3

    References

    • Bioorganic and Medicinal Chemistry, , vol. 20, # 22 p. 6770 - 6789

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.94
  • LogP   3.397
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

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