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CS-W001157 4
Total: USD 88.00

6-Chloropyrazolo[1,5-a]pyridine-3-carboxylic acid

  • CAS No. 1167055-29-9

  • Cat. No. CS-0043057
  • Purity≥97%
  • MDL No.MFCD12405124

*For research and further manufacturing use only, not for direct human use.

6-Chloropyrazolo[1,5-a]pyridine-3-carboxylic acid|CS-0043057

Structure of 1167055-29-9

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General Information

  • CAS No. 1167055-29-9
  • Cat. No. CS-0043057
  • Purity ≥97%
  • MDL No. MFCD12405124
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅ClN₂O₂
  • Molecular Weight 196.59
  • Synonym(s) 6-chloroH-pyrazolo[1,5-a]pyridine-3-carboxylic acid
  • SMILES O=C(C1=C2C=CC(Cl)=CN2N=C1)O

Description

6-Chloropyrazolo[1,5-a]pyridine-3-carboxylic acid is a heterocyclic building block featuring a chlorine-substituted pyrazolopyridine core fused with a carboxylic acid group. This combination delivers enhanced electronic modulation and synthetic versatility for medicinal chemistry applications. The molecule exhibits stability under standard conditions and integrates readily into diverse scaffold architectures via amide coupling or nucleophilic substitution reactions.

Application

6-Chloropyrazolo[1,5-a]pyridine-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. The molecule combines a pyrazolo[1,5-a]pyridine core with strategically positioned chloro and carboxylic acid functionalities, enabling direct derivatization via amide coupling, Suzuki-Miyaura cross-coupling, or nucleophilic substitution. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to diverse analogs in drug discovery campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   54.6
  • LogP   1.6859
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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