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Structure of 1166819-53-9
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6-Bromo-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine features a rigid heteroaromatic core bearing a bromine at the 6-position and a trifluoromethyl group at the 3-position. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a key building block for bioactive triazolopyridine derivatives.
6-Bromo-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine serves as a versatile building block for constructing bioactive heterocycles in medicinal chemistry. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the trifluoromethyl substituent enhances metabolic stability and lipophilicity. The triazolopyridine core provides a rigid, electron-deficient scaffold suitable for targeted molecular design. This compound exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: