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Structure of 41731-52-6
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Ethyl 2-chlorothiazole-4-carboxylate features a reactive chloro-substituted thiazole core paired with an ester handle, enabling direct incorporation into cross-coupling and heterocycle construction workflows. This bench-stable reagent integrates readily into synthetic sequences requiring electrophilic thiazole scaffolds under standard conditions.
Ethyl 2-chlorothiazole-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to thiazole-based scaffolds prevalent in medicinal chemistry. The chlorine atom at the 2-position provides a reliable site for nucleophilic substitution, facilitating coupling with amines, thiols, and other nucleophiles under mild conditions. Its bench-stable nature and compatibility with diverse functional groups make it ideal for modular derivatization in API development and process chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: