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CS-W001157 4
Total: USD 88.00

2-Chloroquinolin-3-amine

  • CAS No. 116632-54-3

  • Cat. No. CS-0134557
  • Purity98+%
  • MDL No.MFCD11656701

*For research and further manufacturing use only, not for direct human use.

2-Chloroquinolin-3-amine|CS-0134557

Structure of 116632-54-3

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General Information

  • CAS No. 116632-54-3
  • Cat. No. CS-0134557
  • Purity 98+%
  • MDL No. MFCD11656701
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇ClN₂
  • Molecular Weight 178.62
  • Synonym(s) 3-AMino-2-chloroquinoline
  • SMILES ClC1=NC2=CC=CC=C2C=C1N

Synthesis

  • Route1
    • tert-Butyl (2-chloroquinolin-3-yl)carbamate|CS-1049990
      742698-74-4
    • ~91%
    • 2-Chloroquinolin-3-amine|CS-0134557
      116632-54-3

    References

    • JANSSEN PHARMACEUTICA N.V. Patent: WO2004/69792 A2, 2004 ; Location in patent: Page 130 ;
  • Route2

    References

    • Ochiai; Yokokawa Yakugaku Zasshi, 1955 , vol. 75, p. 213 Chem.Abstr., 1956 , p. 1819
  • Route3

    References

    • Kokatla, Hari Prasad; Sil, Diptesh; Tanji, Hiromi; Ohto, Umeharu; Malladi, Subbalakshmi S.; Fox, Lauren M.; Shimizu, Toshiyoki; David, Sunil A. ChemMedChem, 2014 , vol. 9, # 4 p. 719 - 723

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.4704
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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