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CS-W001157 4
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(S)-2-Methoxypropan-1-ol

  • CAS No. 116422-39-0

  • Cat. No. CS-0096324
  • Purity≥97%
  • MDL No.MFCD01632593

*For research and further manufacturing use only, not for direct human use.

(S)-2-Methoxypropan-1-ol|CS-0096324

Structure of 116422-39-0

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General Information

  • CAS No. 116422-39-0
  • Cat. No. CS-0096324
  • Purity ≥97%
  • MDL No. MFCD01632593
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀O₂
  • Molecular Weight 90.12
  • Synonym(s) (S)-(+)-2-methoxypropanol
  • SMILES C[C@H](OC)CO

Description

(S)-2-Methoxypropan-1-ol is a chiral alcohol featuring a methoxy group at the C2 position, offering enhanced solubility and stability in polar reaction media. This configuration enables selective functionalization in asymmetric synthesis, particularly in the construction of complex oxygenated scaffolds. Its bench-stable nature supports reliable use across diverse transformation conditions.

Application

(S)-2-Methoxypropan-1-ol serves as a chiral building block for asymmetric synthesis, offering reliable stereochemical control in the construction of β-amino alcohols and other bioactive scaffolds. Its bench-stable nature, combined with excellent functional group tolerance, facilitates straightforward derivatization via etherification or oxidation. The molecule functions effectively as a precursor in catalytic transformations and provides a robust handle for purification and structural verification in complex synthetic sequences.

Synthesis

  • Route1
    • (S)-Methyl 2-methoxypropanoate|CS-0541735
      54656-65-4
    • ~%
    • In-stock
      (S)-2-Methoxypropan-1-ol|CS-0096324
      116422-39-0

    References

    • Journal of Organic Chemistry, , vol. 58, # 25 p. 7038 - 7044
  • Route2
    • (2S)-2-Methoxypropanoic acid ethyl ester|CS-0098051
      41918-08-5
    • ~70%
    • In-stock
      (S)-2-Methoxypropan-1-ol|CS-0096324
      116422-39-0

    References

    • Steudel, Annette; Stehr, Jens; Siebel, Eric; Fischer, R. Dieter Journal of Organometallic Chemistry, 1998 , vol. 570, # 1 p. 89 - 96
  • Route3
    • null|null
      4324-39-4
    • ~%
    • In-stock
      (S)-2-Methoxypropan-1-ol|CS-0096324
      116422-39-0
    • In-stock
      (R)-2-Methoxypropan-1-ol|CS-W011349
      6131-59-5

    References

    • Journal of the Chemical Society - Perkin Transactions 1, , # 12 p. 1467 - 1479

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.0136
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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