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Structure of 1160936-52-6
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1-(5-Bromo-3-fluoropyridin-2-yl)ethan-1-one features a bromo and fluoro substituent on a pyridine ring, delivering enhanced electron-withdrawing character and improved stability. This ketone integrates readily into cross-coupling reactions, enabling efficient construction of complex heterocyclic architectures under standard conditions.
1-(5-Bromo-3-fluoropyridin-2-yl)ethan-1-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of complex heterocyclic scaffolds. Its bromo and fluoro substituents provide orthogonal reactivity for palladium-catalyzed cross-coupling and electrophilic substitution reactions. The acetyl group offers a handle for further functionalization via enolization or nucleophilic addition. Bench-stable and readily purified by flash chromatography, it facilitates scalable synthesis in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: