1-(6-bromo-3-fluoropyridin-2-yl)ethan-1-one

Name: 1-(6-bromo-3-fluoropyridin-2-yl)ethan-1-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1016228-01-5
Cat. No. CS-W000628
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(6-bromo-3-fluoropyridin-2-yl)ethan-1-one|CS-W000628

Structure of 1016228-01-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1016228-01-5
Cat. No. CS-W000628
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅BrFNO
Molecular Weight 218.02
Synonym(s) 1-(6-Bromo-3-fluoro-pyridin-2-yl)-ethanone
SMILES Brc1ccc(c(n1)C(=O)C)F

Description

1-(6-Bromo-3-fluoropyridin-2-yl)ethan-1-one features a bromo-fluoro-substituted pyridine core paired with an acetyl group, delivering a robust scaffold for late-stage functionalization. This electron-deficient heterocycle integrates seamlessly into cross-coupling reactions and enables efficient access to complex pharmaceutical intermediates under standard conditions.

Application

1-(6-Bromo-3-fluoropyridin-2-yl)ethan-1-one serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The ortho-bromo and meta-fluoro substituents provide complementary reactivity for sequential derivatization, while the acetyl group offers a handle for further transformations such as enolization or nucleophilic substitution. Its bench-stable nature and compatibility with standard synthetic workflows make it ideal for constructing complex heterocyclic scaffolds and API intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.96
LogP 2.1858
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Ketone

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

1016228-01-5 sigma1016228-01-5 manufacturer1016228-01-5 price1016228-01-5 structure1016228-01-5 SDSbuy 1016228-01-51016228-01-5 supplier1016228-01-5 uses1016228-01-5 molecular weightprice of 1016228-01-51016228-01-5 chemical name formula of 1016228-01-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(6-bromo-3-fluoropyridin-2-yl)ethan-1-one

CAS No. 1016228-01-5

Recommended Products