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CS-W001157 4
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4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile

  • CAS No. 1159982-14-5

  • Cat. No. CS-W006947
  • Purity≥97%
  • MDL No.MFCD11046238

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile|CS-W006947

Structure of 1159982-14-5

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General Information

  • CAS No. 1159982-14-5
  • Cat. No. CS-W006947
  • Purity ≥97%
  • MDL No. MFCD11046238
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄BrN₃
  • Molecular Weight 222.04
  • Synonym(s) 4-Bromo-7-azaindole-3-carbonitrile
  • SMILES N#CC1=CNC2=NC=CC(Br)=C21

Description

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile is a heteroaromatic building block featuring a bromine atom and a nitrile group positioned for orthogonal functionalization. This scaffold enables direct incorporation into cross-coupling reactions and facilitates the synthesis of complex nitrogen-containing frameworks in medicinal chemistry and materials science.

Application

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile serves as a versatile building block for the synthesis of functionalized heterocycles in medicinal chemistry and materials science. Its bromo and nitrile groups enable palladium-catalyzed cross-coupling reactions and nucleophilic transformations, offering high stability under standard bench conditions and compatibility with diverse reaction workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.47
  • LogP   2.19708
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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