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CS-W001157 4
Total: USD 88.00

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

  • CAS No. 1000340-36-2

  • Cat. No. CS-0044362
  • Purity≥97%
  • MDL No.MFCD09880127

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid|CS-0044362

Structure of 1000340-36-2

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General Information

  • CAS No. 1000340-36-2
  • Cat. No. CS-0044362
  • Purity ≥97%
  • MDL No. MFCD09880127
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrN₂O₂
  • Molecular Weight 241.04
  • Synonym(s) 4-BROMO-7-AZAINDOLE-3-CARBOXYLIC ACID
  • SMILES O=C(C1=CNC2=NC=CC(Br)=C21)O

Description

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid features a fused heterocyclic core with a brominated pyrrole ring and a carboxylic acid at the 3-position. This scaffold serves as a key building block in medicinal chemistry, offering enhanced metabolic stability and enabling direct coupling reactions for drug discovery applications.

Application

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid serves as a versatile building block for constructing biologically relevant heterocycles. Its bromo and carboxylic acid functionalities enable direct cross-coupling reactions and facile derivatization, supporting efficient access to complex scaffolds in medicinal chemistry. The compound exhibits good bench stability and is compatible with standard purification protocols, facilitating integration into multi-step synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.98
  • LogP   2.0236
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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