6-Bromoimidazo[1,2-b]pyridazine

Name: 6-Bromoimidazo[1,2-b]pyridazine
Brand: ChemScene
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CAS No. 1159977-65-7
Cat. No. CS-0043075
Purity≥98%
MDL No.MFCD12198219

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromoimidazo[1,2-b]pyridazine|CS-0043075

Structure of 1159977-65-7

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Description

6-Bromoimidazo[1,2-b]pyridazine is a heterocyclic building block featuring a bromine substituent at the 6-position of an imidazo[1,2-b]pyridazine core. This electron-deficient scaffold integrates readily into transition-metal-catalyzed coupling reactions, enabling efficient access to functionalized polycyclic architectures. The bromine moiety serves as a versatile handle for further derivatization under standard conditions.

Application

6-Bromoimidazo[1,2-b]pyridazine serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions with broad functional group tolerance. Its bromine substituent facilitates efficient derivatization in Suzuki, Stille, and Negishi protocols, while the imidazopyridazine core provides structural rigidity and pharmacophoric potential. The compound exhibits excellent bench stability and ease of purification, making it well-suited for medicinal chemistry campaigns and API intermediate development.

General Information

CAS No. 1159977-65-7
Cat. No. CS-0043075
Purity ≥98%
MDL No. MFCD12198219
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄BrN₃
Molecular Weight 198.02
Synonym(s) 6-BroMoiMidazo[1,2-b]pyridazin
SMILES BrC1=NN2C=CN=C2C=C1

Computational Chemistry Data

TPSA 30.19
LogP 1.4918
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridazine compounds

Key Words

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6-Bromoimidazo[1,2-b]pyridazine

CAS No. 1159977-65-7

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