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Structure of 1159821-66-5
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6-Cyclopropylpyridin-3-amine features a pyridine core functionalized with a cyclopropyl group at the 6-position and a primary amine at the 3-position. This configuration imparts enhanced lipophilicity and metabolic stability, making it a valuable scaffold in medicinal chemistry for kinase inhibitors and CNS-targeted therapeutics. The cyclic amine moiety enables hydrogen bonding and coordination in biological binding pockets.
6-Cyclopropylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling reactions. Its pyridine core offers favorable electronic properties for metal-catalyzed transformations, while the cyclopropyl group provides steric modulation and metabolic stability. The primary amine facilitates rapid derivatization, and the compound exhibits excellent bench stability and ease of purification, making it well-suited for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: