(R)-(4-Methylmorpholin-2-yl)methanol

Name: (R)-(4-Methylmorpholin-2-yl)methanol
Brand: ChemScene
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CAS No. 1159598-35-2
Cat. No. CS-0061774
Purity≥97%
MDL No.MFCD16294696

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(R)-(4-Methylmorpholin-2-yl)methanol|CS-0061774

Structure of 1159598-35-2

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General Information

CAS No. 1159598-35-2
Cat. No. CS-0061774
Purity ≥97%
MDL No. MFCD16294696
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO₂
Molecular Weight 131.17
Synonym(s) (R)-4-Methyl-2-(hydroxymethyl)morpholine
SMILES OC[C@H]1CN(C)CCO1

Description

(R)-(4-Methylmorpholin-2-yl)methanol is a chiral building block featuring a stereodefined morpholine ring with a pendant hydroxymethyl group. This configuration imparts enhanced solubility and stability in polar reaction media, enabling efficient incorporation into complex molecular architectures. The compound serves as a key intermediate in the synthesis of bioactive molecules and functional polymers.

Application

(R)-(4-Methylmorpholin-2-yl)methanol serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and functionalization protocols. Its bench-stable nature, combined with favorable solubility and compatibility with common protecting group strategies, facilitates efficient route development. The molecule functions as a key scaffold component in targeted compound libraries, particularly for kinase inhibitors and CNS-active agents, where stereochemical control is essential.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 32.7
LogP -0.6907
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Key Words

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(R)-(4-Methylmorpholin-2-yl)methanol

CAS No. 1159598-35-2

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