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*For research and further manufacturing use only, not for direct human use.
Structure of 1159531-18-6
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This protected lysine derivative features a fluorenylmethoxycarbonyl group at the Nα position and a pent-4-ynoyl moiety at the Nε terminus, enabling orthogonal functionalization in peptide synthesis. The fluoren-9-yl methoxycarbonyl (Fmoc) handle ensures stable, acid-labile protection, while the terminal alkyne facilitates bioorthogonal coupling via copper-catalyzed azide-alkyne cycloaddition. This structure supports modular assembly of complex peptides and conjugates under standard conditions.
N₂-(((9H-fluoren-9-yl)methoxy)carbonyl)-N⁶-(pent-4-ynoyl)-L-lysine serves as a versatile dipeptide building block for solid-phase peptide synthesis, combining the orthogonal Fmoc group for Nα protection with a terminal alkyne functionality. The pent-4-ynoyl side chain enables bioorthogonal conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating site-specific labeling or macrocyclization. Its bench-stable, crystalline nature and compatibility with standard coupling protocols make it ideal for modular peptide assembly and probe development in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: