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CS-W001157 4
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4-(Aminomethyl)-N,N-dimethyltetrahydro-2H-pyran-4-amine dihydrochloride

  • CAS No. 1158792-81-4

  • Cat. No. CS-0069619
  • Molecule weight231.16
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Aminomethyl)-N,N-dimethyltetrahydro-2H-pyran-4-amine dihydrochloride|CS-0069619

Structure of 1158792-81-4

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General Information

  • CAS No. 1158792-81-4
  • Cat. No. CS-0069619
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₂₀Cl₂N₂O
  • Molecular Weight 231.16
  • Synonym(s) 1158792-81-4
  • SMILES NCC1(N(C)C)CCOCC1.[H]Cl.[H]Cl

Description

This tetrahydro-2H-pyranamine derivative features a pendant aminomethyl group and dimethylamino functionality, delivering enhanced solubility and nucleophilicity. The dihydrochloride salt form ensures stability and ease of handling under standard conditions. Ideal for constructing bifunctional scaffolds in medicinal chemistry and peptide conjugation workflows.

Application

4-(Aminomethyl)-N,N-dimethyltetrahydro-2H-pyran-4-amine dihydrochloride serves as a versatile bifunctional building block for medicinal chemistry and peptide conjugation. The tertiary amine and primary amine functionalities enable efficient derivatization, while the tetrahydropyran ring provides metabolic stability and conformational control. Its dihydrochloride salt form enhances solubility and handling stability, facilitating use in standard coupling reactions and solid-phase synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   38.49
  • LogP   0.8995
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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