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CS-W001157 4
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tert-Butyl 2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate

  • CAS No. 1158749-94-0

  • Cat. No. CS-W007181
  • Molecule weight254.33
  • Purity≥96%
  • MDL No.MFCD12198560

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate|CS-W007181

Structure of 1158749-94-0

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General Information

  • CAS No. 1158749-94-0
  • Cat. No. CS-W007181
  • Purity ≥96%
  • MDL No. MFCD12198560
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₂N₂O₃
  • Molecular Weight 254.33
  • Synonym(s) None
  • SMILES CC(C)(C)OC(N(CC1)CCC1(CC2)NC2=O)=O

Description

tert-Butyl 2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate features a rigid spirocyclic scaffold with dual nitrogen atoms and a carbonyl group, enabling precise spatial control in synthetic transformations. This bench-stable, moisture-tolerant reagent integrates readily into complex molecular architectures, particularly in medicinal chemistry applications requiring constrained heterocyclic motifs.

Application

tert-Butyl 2-oxo-1,8-diazaspiro[4.5]decane-8-carboxylate serves as a versatile spirocyclic building block for the synthesis of complex nitrogen-containing heterocycles. Its stable tert-butyl ester and ketone functionalities enable sequential functionalization, including reductive amination and nucleophilic addition. The rigid spirocyclic core provides defined stereochemistry and enhances metabolic stability in medicinal chemistry applications, facilitating efficient access to bioactive scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.64
  • LogP   1.6661
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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