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CS-W001157 4
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(R)-Methyl 2-amino-6-(((benzyloxy)carbonyl)amino)hexanoate hydrochloride

  • CAS No. 1158-35-6

  • Cat. No. CS-0372348
  • Molecule weight330.81
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-Methyl 2-amino-6-(((benzyloxy)carbonyl)amino)hexanoate hydrochloride|CS-0372348

Structure of 1158-35-6

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General Information

  • CAS No. 1158-35-6
  • Cat. No. CS-0372348
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₃ClN₂O₄
  • Molecular Weight 330.81
  • Synonym(s) H-D-Lys(Z)-OMe HCl
  • SMILES COC([C@H](N)CCCCNC(OCC1=CC=CC=C1)=O)=O.Cl

Description

(R)-Methyl 2-amino-6-(((benzyloxy)carbonyl)amino)hexanoate hydrochloride serves as a chiral building block for peptide synthesis, featuring a protected α-amino group and a pendant benzyloxycarbonyl moiety. This bench-stable derivative facilitates efficient coupling reactions under standard conditions, enabling streamlined access to complex peptide architectures with high diastereoselectivity.

Application

(R)-Methyl 2-amino-6-(((benzyloxy)carbonyl)amino)hexanoate hydrochloride serves as a key chiral building block for the synthesis of bioactive heterocycles and peptide-derived scaffolds. Its amine and ester functionalities enable straightforward coupling reactions, while the benzyloxycarbonyl (Cbz) group provides robust protection under standard conditions. The hydrochloride salt enhances solubility and stability in aqueous and polar organic media, facilitating purification and handling in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352-P304+P340

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   2.0052
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   8

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