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Structure of 1156542-30-1
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2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine features a strategically positioned trifluoromethyl group that enhances electron deficiency and metabolic stability. This halogenated pyridine serves as a pivotal building block in medicinal chemistry, enabling efficient coupling reactions for targeted synthesis of bioactive compounds.
2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The trifluoromethyl and fluorine substituents enhance metabolic stability and modulate electronic properties, while the bromine facilitates reliable C–C bond formation under standard conditions. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: