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Structure of 1150561-77-5
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Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate is a bench-stable boronate ester featuring a terminal methyl ester group. This structure enables direct coupling in Suzuki-Miyaura reactions, streamlining the synthesis of functionalized alkenes and aromatic derivatives. The tetramethyl-substituted dioxaborolane enhances stability and minimizes side reactions during handling and storage.
Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate moiety enables efficient coupling with aryl and vinyl halides under mild conditions, while the ester group provides a handle for downstream functionalization. Its excellent stability, low toxicity, and ease of purification make it a practical choice for constructing complex molecular architectures in medicinal chemistry and materials science workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: