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Structure of 1150114-52-5
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This boronic acid features a fluorinated aryl ring paired with a hydroxyl group, enabling selective functionalization in cross-coupling reactions. The ortho-fluoro substitution enhances stability and modulates reactivity, while the pendant hydroxyl facilitates solubility and downstream derivatization. A bench-stable reagent for constructing complex phenolic architectures under standard conditions.
(2-Fluoro-5-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-fluoro and phenolic hydroxyl groups provide enhanced reactivity and directing effects, while the boronic acid moiety offers good bench stability and compatibility with diverse functional groups. This compound facilitates rapid access to fluorinated aromatic systems relevant in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: