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CS-W001157 4
Total: USD 88.00

2,5-Dimethoxyterephthalohydrazide

  • CAS No. 114503-42-3

  • Cat. No. CS-0146314
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,5-Dimethoxyterephthalohydrazide|CS-0146314

Structure of 114503-42-3

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General Information

  • CAS No. 114503-42-3
  • Cat. No. CS-0146314
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄N₄O₄
  • Molecular Weight 254.24
  • Synonym(s) 1,4-Benzenedicarboxylic acid, 2,5-dimethoxy-, 1,4-dihydrazide
  • SMILES O=C(NN)C1=C(OC)C=C(C(NN)=O)C(OC)=C1

Description

2,5-Dimethoxyterephthalohydrazide features a rigid aromatic core with two methoxy groups and hydrazide functionalities, enabling precise coordination in metal complexation and serving as a key scaffold for bioactive heterocycles.

Application

2,5-Dimethoxyterephthalohydrazide serves as a versatile building block for heterocyclic synthesis, particularly in the construction of pyrazole and triazole scaffolds via hydrazide condensation reactions. Its ortho-dicarbonyl framework with methoxy substituents enhances solubility and stability, facilitating straightforward purification and broad functional group tolerance. The compound functions effectively in standard coupling protocols, enabling efficient access to bioactive core structures relevant to medicinal chemistry campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   128.7
  • LogP   -1.0892
  • H_Acceptors   6
  • H_Donors   4
  • Rotatable_Bonds   4

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