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CS-W001157 4
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2,5-Diethoxyterephthalohydrazide

  • CAS No. 1136292-71-1

  • Cat. No. CS-0111213
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,5-Diethoxyterephthalohydrazide|CS-0111213

Structure of 1136292-71-1

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General Information

  • CAS No. 1136292-71-1
  • Cat. No. CS-0111213
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈N₄O₄
  • Molecular Weight 282.30
  • Synonym(s) 2,5-diethoxybenzene-1,4-dicarbohydrazide
  • SMILES O=C(C1=CC(OCC)=C(C(NN)=O)C=C1OCC)NN

Description

2,5-Diethoxyterephthalohydrazide features a rigid aromatic core with two ethoxy groups flanking a hydrazide-functionalized terephthalate scaffold. This configuration enables robust coordination in metal-organic frameworks and facilitates selective conjugation in bioconjugation workflows under standard conditions.

Application

2,5-Diethoxyterephthalohydrazide serves as a versatile building block for the synthesis of heterocyclic scaffolds and hydrazide-based functional materials. Its two ethoxy groups enhance solubility and stability in organic media, while the hydrazide moiety enables reliable condensation reactions with aldehydes and ketones to form pyrazole and triazole derivatives. The molecule exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and materials development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   128.7
  • LogP   -0.309
  • H_Acceptors   6
  • H_Donors   4
  • Rotatable_Bonds   6

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