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Structure of 1142211-17-3
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tert-Butyl (1-(hydroxymethyl)cyclobutyl)carbamate delivers a protected hydroxymethylcyclobutyl moiety with enhanced stability and solubility. This bench-stable carbamate features a pendant hydroxymethyl group enabling downstream functionalization, while the tert-butyl protection ensures compatibility with standard deprotection protocols in synthetic workflows.
tert-Butyl (1-(hydroxymethyl)cyclobutyl)carbamate serves as a stable, bench-friendly carbamate protecting group for primary amines, enabling selective functionalization of cyclobutylamine derivatives. The hydroxymethyl side chain provides a versatile handle for further derivatization, including oxidation to aldehydes or carboxylic acids, while the tert-butyl group ensures facile acid-mediated deprotection under mild conditions. Its compatibility with standard coupling and reduction protocols makes it a practical choice in medicinal chemistry synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: