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CS-W001157 4
Total: USD 88.00

(2R,3R)-1,4-Dioxaspiro[4.5]decane-2,3-diylbis(diphenylmethanol)

  • CAS No. 114026-76-5

  • Cat. No. CS-0086920
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2R,3R)-1,4-Dioxaspiro[4.5]decane-2,3-diylbis(diphenylmethanol)|CS-0086920

Structure of 114026-76-5

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General Information

  • CAS No. 114026-76-5
  • Cat. No. CS-0086920
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₄H₃₄O₄
  • Molecular Weight 506.63
  • Synonym(s) (2R,3R)-α2,α2,α3,α3-tetraphenyl-1,4-Dioxaspiro[4.5]decane-2,3-diMethanol
  • SMILES OC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@H]3[C@H](C(C4=CC=CC=C4)(C5=CC=CC=C5)O)OC6(CCCCC6)O3

Description

This spirocyclic diol features two diphenylmethyl groups tethered via a rigid 1,4-dioxaspiro[4.5]decane scaffold, offering exceptional stereochemical stability and enhanced solubility in polar aprotic solvents. The defined (2R,3R) configuration enables predictable stereocontrol in asymmetric synthesis, particularly in chiral auxiliaries or catalyst design.

Application

(2R,3R)-1,4-Dioxaspiro[4.5]decane-2,3-diylbis(diphenylmethanol) serves as a rigid, chiral bisbenzhydryl scaffold enabling stereoselective synthesis of complex polyfunctional molecules. Its spirocyclic core exhibits excellent bench stability and facilitates efficient purification via crystallization. The molecule functions effectively in standard coupling reactions and provides a robust platform for constructing heterocyclic systems and drug-like scaffolds with defined stereochemistry.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   6.303
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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