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CS-W001157 4
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4-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

  • CAS No. 1137278-45-5

  • Cat. No. CS-M0483
  • Molecule weight236.70
  • Purity≥98%
  • MDL No.MFCD20482716

*For research and further manufacturing use only, not for direct human use.

4-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole|CS-M0483

Structure of 1137278-45-5

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General Information

  • CAS No. 1137278-45-5
  • Cat. No. CS-M0483
  • Purity ≥98%
  • MDL No. MFCD20482716
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₃ClN₂O
  • Molecular Weight 236.70
  • Synonym(s) 1H-Indazole, 4-chloro-1-(tetrahydro-2H-pyran-2-yl)-
  • SMILES ClC1=CC=CC2=C1C=NN2C3OCCCC3

Synthesis

  • Route1

    References

    • Genentech, Inc.; Heald, Robert Andrew; McLean, Neville James Patent: US2014/65136 A1, 2014 ; Location in patent: Paragraph 0189 ;
  • Route2
    • null|null
      110-87-2
    • In-stock
      4-Chloro-1H-indazole|CS-M0440
      13096-96-3
    • ~%
    • 4-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole|CS-M0483
      1137278-45-5
    • null|null
      1146955-34-1

    References

    • Tian, Qingping; Cheng, Zhigang; Yajima, Herbert M.; Savage, Scott J.; Green, Keena L.; Humphries, Theresa; Reynolds, Mark E.; Babu, Srinivasan; Gosselin, Francis; Askin, David; Kurimoto, Isao; Hirata, Norihiko; Iwasaki, Mitsuhiro; Shimasaki, Yasuharu; Miki, Takashi Organic Process Research and Development, 2013 , vol. 17, # 1 p. 97 - 107
  • Route3

    References

    • Genentech, Inc.; Heald, Robert Andrew; McLean, Neville James Patent: US2014/65136 A1, 2014 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   27.05
  • LogP   3.3888
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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