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CS-W001157 4
Total: USD 88.00

1-(3,4-Dimethoxyphenyl)ethanone

  • CAS No. 1131-62-0

  • Cat. No. CS-W005151
  • Purity≥98%
  • MDL No.MFCD00008737

*For research and further manufacturing use only, not for direct human use.

1-(3,4-Dimethoxyphenyl)ethanone|CS-W005151

Structure of 1131-62-0

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General Information

  • CAS No. 1131-62-0
  • Cat. No. CS-W005151
  • Purity ≥98%
  • MDL No. MFCD00008737
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₃
  • Molecular Weight 180.20
  • Synonym(s) Ethanone, 1-(3,4-dimethoxyphenyl)-; 1-(3,4-Dimethoxyphenyl)ethanone
  • SMILES CC(C1=CC=C(OC)C(OC)=C1)=O

Description

1-(3,4-Dimethoxyphenyl)ethanone features a benzene ring bearing two methoxy groups in the 3,4-positions, delivering enhanced solubility and stability. This electron-rich aryl ketone integrates readily into synthetic pathways requiring aromatic electrophiles or coupling partners. The acetyl moiety enables direct functionalization or reduction to the corresponding alcohol.

Application

1-(3,4-Dimethoxyphenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through standard functional group transformations. Its aryl ketone functionality exhibits robust bench stability and compatibility with common reaction conditions, facilitating coupling reactions, reductions, and electrophilic substitutions. The dimethoxy substitution pattern enhances solubility and provides predictable reactivity for downstream derivatization in API synthesis workflows.

Synthesis

  • Route1
    • null|null
      75906-45-5
    • ~96%
    • In-stock
      1-(3,4-Dimethoxyphenyl)ethanone|CS-W005151
      1131-62-0

    References

    • Kim, Bo Ram; Lee, Hyung-Geun; Kim, Eun Jung; Lee, Sang-Gyeong; Yoon, Yong-Jin Journal of Organic Chemistry, 2010 , vol. 75, # 2 p. 484 - 486
  • Route2
    • 1-(3,4-Dimethoxyphenyl)ethan-1-ol|CS-0378428
      5653-65-6
    • ~96%
    • In-stock
      1-(3,4-Dimethoxyphenyl)ethanone|CS-W005151
      1131-62-0

    References

    • Mohammadpoor-Baltork, Iraj; Sadeghi, Majid M.; Adibi, Abol-Hassan Molecules, 2001 , vol. 6, # 11 p. 900 - 908
  • Route3
    • 1,2-Dimethoxybenzene Methoxamine  Impurity|CS-0229041
      91-16-7
    • null|null
      108-24-7
    • ~93%
    • In-stock
      1-(3,4-Dimethoxyphenyl)ethanone|CS-W005151
      1131-62-0

    References

    • Arai, Shigeru; Sudo, Yukinori; Nishida, Atsushi Tetrahedron, 2005 , vol. 61, # 19 p. 4639 - 4642

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.9064
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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