Ethyl 2-chloro-6-hydroxybenzoate

Name: Ethyl 2-chloro-6-hydroxybenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 112270-06-1
Cat. No. CS-W018896
Purity≥97%
MDL No.MFCD09038111

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-chloro-6-hydroxybenzoate|CS-W018896

Structure of 112270-06-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 112270-06-1
Cat. No. CS-W018896
Purity ≥97%
MDL No. MFCD09038111
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₉ClO₃
Molecular Weight 200.62
Synonym(s) PO20090710-P-570
SMILES ClC1=C(C(=O)OCC)C(=CC=C1)O

Description

Ethyl 2-chloro-6-hydroxybenzoate features a hydroxyl group ortho to the ester and a chlorine substituent at the para position, enabling selective derivatization. This electron-deficient aromatic scaffold integrates readily into synthetic sequences requiring orthogonal functional handles. The molecule exhibits enhanced stability under standard conditions and tolerates a range of reaction environments.

Application

Ethyl 2-chloro-6-hydroxybenzoate serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the phenolic hydroxyl group while maintaining compatibility with standard coupling and protection strategies. The ortho-chloro substituent facilitates palladium-catalyzed cross-coupling reactions, and the ester functionality supports selective transformations under mild conditions. Bench-stable and amenable to purification via recrystallization or column chromatography, it functions effectively in multi-step syntheses of heterocyclic scaffolds and bioactive molecules.

Synthesis

Route1
- In-stock
  
  172217-11-7
- ~75%
- In-stock
  
  112270-06-1
References
- Ple, Patrick A.; Green, Tim P.; Hennequin, Laurent F.; Curwen, Jon; Fennell, Michael; Allen, Jack; Lambert-Van Der Brempt, Christine; Costello, Gerard Journal of Medicinal Chemistry, 2004 , vol. 47, # 4 p. 871 - 887
Route2
- 7664-93-9
- In-stock
  
  172217-11-7
- ~%
- In-stock
  
  112270-06-1
References
- EP1292594 B1, ;
Route3
- In-stock
  
  7335-25-3
- ~77%
- In-stock
  
  112270-06-1
References
- Yang, Yiqing; Lin, Yun; Rao, Yu Organic Letters, 2012 , vol. 14, # 11 p. 2874 - 2877

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2810
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 46.53
LogP 2.2223
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Ethyl 2-chloro-6-hydroxybenzoate sigmaEthyl 2-chloro-6-hydroxybenzoate manufacturerEthyl 2-chloro-6-hydroxybenzoate priceEthyl 2-chloro-6-hydroxybenzoate structureEthyl 2-chloro-6-hydroxybenzoate SDSbuy Ethyl 2-chloro-6-hydroxybenzoateEthyl 2-chloro-6-hydroxybenzoate supplierEthyl 2-chloro-6-hydroxybenzoate usesEthyl 2-chloro-6-hydroxybenzoate molecular weightprice of Ethyl 2-chloro-6-hydroxybenzoateEthyl 2-chloro-6-hydroxybenzoate chemical name formula of Ethyl 2-chloro-6-hydroxybenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Ethyl 2-chloro-6-hydroxybenzoate

CAS No. 112270-06-1

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words