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Structure of 1122-47-0
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1-Methylcytosine is a modified cytosine derivative featuring a methyl group at the C5 position, enhancing its stability and altering base-pairing dynamics. This epigenetic mark plays a critical role in DNA methylation studies, offering a reliable model for investigating gene silencing mechanisms and chromatin regulation.
1-Methylcytosine serves as a stable, bench-ready nucleobase analog that facilitates site-specific DNA/RNA methylation studies. Its methyl group at the C1 position enhances resistance to enzymatic degradation while preserving Watson-Crick base pairing with guanine. This compound enables straightforward incorporation into oligonucleotides via standard phosphoramidite chemistry and functions reliably in PCR, sequencing, and hybridization assays without requiring specialized handling or activation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: