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CS-W001157 4
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Ethyleneglycoldi-n-butylether

  • CAS No. 112-48-1

  • Cat. No. CS-0187426
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyleneglycoldi-n-butylether|CS-0187426

Structure of 112-48-1

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General Information

  • CAS No. 112-48-1
  • Cat. No. CS-0187426
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₂O₂
  • Molecular Weight 174.28
  • Synonym(s) Ethylene glycol dibutyl ether
  • SMILES CCCCOCCOCCCC

Description

Ethyleneglycoldi-n-butylether is a bench-stable, moisture-tolerant solvent featuring two alkoxy chains that enhance solubility in both polar and nonpolar media. This ether delivers efficient phase transfer capabilities in synthetic workflows, particularly in organometallic reactions and catalytic transformations requiring low viscosity and high thermal stability.

Application

Ethyleneglycoldi-n-butylether serves as a stable, low-viscosity solvent enabling efficient phase transfer and solubilization in organic synthesis. It functions effectively in nucleophilic substitutions, Grignard reactions, and transition-metal-catalyzed couplings due to its excellent functional group tolerance and compatibility with reactive intermediates. Its bench-stable nature and ease of removal via distillation or extraction make it a practical choice for scalable laboratory workflows.

Synthesis

  • Route1
    • null|null
      3390-13-4
    • ~%
    • null|null
      111-76-2
    • In-stock
      Ethyleneglycoldi-n-butylether|CS-0187426
      112-48-1

    References

    • US2012/330066 A1, ; Page/Page column 11 ;
  • Route2
    • In-stock
      Ethylene glycol,98%|CS-0015059
      107-21-1
    • null|null
      123-72-8
    • ~7%
    • null|null
      111-76-2
    • In-stock
      Ethyleneglycoldi-n-butylether|CS-0187426
      112-48-1
    • null|null
      71-36-3

    References

    • US2010/48940 A1, ; Page/Page column 6-7 ;
  • Route3
    • 1-(Chloromethoxy)butane|CS-0517473
      2351-69-1
    • ~%
    • In-stock
      Ethyleneglycoldi-n-butylether|CS-0187426
      112-48-1

    References

    • Journal of the American Chemical Society, , vol. 76, p. 3728 Bulletin de la Societe Chimique de France, , p. 199

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H313-H316-H413
Precautionary Statements : P210-P273-P280-P370+P378-P403-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.6198
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   9

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