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CS-W001157 4
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6-Bromo-2-fluoro-3-methylbenzaldehyde

  • CAS No. 1114809-22-1

  • Cat. No. CS-0187776
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-2-fluoro-3-methylbenzaldehyde|CS-0187776

Structure of 1114809-22-1

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General Information

  • CAS No. 1114809-22-1
  • Cat. No. CS-0187776
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrFO
  • Molecular Weight 217.04
  • Synonym(s) None
  • SMILES CC1=C(C(=C(C=C1)Br)C=O)F

Description

6-Bromo-2-fluoro-3-methylbenzaldehyde features a trifunctional aromatic core with bromine, fluorine, and methyl groups positioned for orthogonal reactivity. This electron-deficient aldehyde integrates readily into cross-coupling cascades and serves as a key intermediate in the synthesis of bioactive heterocycles and functionalized pharmaceutical scaffolds under standard conditions.

Application

6-Bromo-2-fluoro-3-methylbenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of halogenated aryl motifs with orthogonal reactivity. The aldehyde group facilitates nucleophilic additions and condensation reactions, while the bromo and fluoro substituents support palladium-catalyzed cross-coupling processes. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for multi-step synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.70912
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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