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(R)-Bn-Pyox

  • CAS No. 1108603-35-5

  • Cat. No. CS-0087132
  • Molecule weight238.28
  • Purity≥95%
  • MDL No.MFCD30541660

*For research and further manufacturing use only, not for direct human use.

(R)-Bn-Pyox|CS-0087132

Structure of 1108603-35-5

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General Information

  • CAS No. 1108603-35-5
  • Cat. No. CS-0087132
  • Purity ≥95%
  • MDL No. MFCD30541660
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₄N₂O
  • Molecular Weight 238.28
  • Synonym(s) 2-[(4R)-4,5-dihydro-4-(phenylMethyl)-2-oxazolyl]- Pyridine
  • SMILES C1(C2=N[C@H](CC3=CC=CC=C3)CO2)=NC=CC=C1

Description

(R)-Bn-Pyox features a chiral pyrrolidinone scaffold with a benzyl-protected amine, enabling direct incorporation into asymmetric synthesis. This bench-stable, moisture-tolerant building block facilitates stereoselective transformations under standard conditions.

Application

(R)-Bn-Pyox serves as a robust chiral auxiliary in asymmetric synthesis, enabling stereoselective enolate formation and C–C bond construction. Its benzyl-protected pyrrolidine oxazolidinone framework exhibits excellent bench stability, facile handling, and compatibility with diverse functional groups. Widely employed in the synthesis of non-proteinogenic amino acids and bioactive heterocycles, it facilitates high diastereoselectivity in aldol and alkylation reactions under mild conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.48
  • LogP   2.4697
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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