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CS-W001157 4
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3-(2-Methoxyphenyl)pyrrolidine hydrochloride

  • CAS No. 1106941-26-7

  • Cat. No. CS-0150308
  • Purity≥97%
  • MDL No.MFCD03701258

*For research and further manufacturing use only, not for direct human use.

3-(2-Methoxyphenyl)pyrrolidine hydrochloride|CS-0150308

Structure of 1106941-26-7

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General Information

  • CAS No. 1106941-26-7
  • Cat. No. CS-0150308
  • Purity ≥97%
  • MDL No. MFCD03701258
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆ClNO
  • Molecular Weight 213.70
  • Synonym(s) None
  • SMILES COC1=CC=CC=C1C2CCNC2.Cl

Description

This pyrrolidine derivative features a 2-methoxyphenyl group conjugated to the nitrogen, enhancing lipophilicity and metabolic stability. The hydrochloride salt improves solubility and handling under standard conditions, making it suitable for medicinal chemistry applications requiring balanced physicochemical properties.

Application

3-(2-Methoxyphenyl)pyrrolidine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to biologically active scaffolds. The pyrrolidine core provides a rigid, chiral amine framework with favorable solubility and metabolic stability. Its ortho-methoxyphenyl substituent offers a handle for further functionalization via cross-coupling or oxidation reactions. The hydrochloride salt enhances bench stability, simplifies purification, and improves handling in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   2.1939
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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